Hedgehog Pathway and Pediatric Nonalcoholic Fatty Liver Disease

It is unclear why the histology of pediatric and adult nonalcoholic fatty liver disease sometimes differs. In adults, severity of portal inflammation and fibrosis correlate with Hedgehog pathway activity. Hedgehog (Hh) signaling regulates organogenesis, but is silent in adult livers until injury re-...

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Main Authors: Swiderska-Syn, Marzena, Suzuki, Ayako, Guy, Cynthia D., Schwimmer, Jeffrey B., Abdelmalek, Manal F., Levine, Joel E., Diehl, Anna Mae
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637920/
https://ncbi.nlm.nih.gov/pubmed/23300059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26230
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