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Hedgehog Pathway Activation Parallels Histologic Severity of Injury and Fibrosis in Human Nonalcoholic Fatty Liver Disease

The Hedgehog (Hh) signaling pathway mediates several processes that are deregulated in patients with the metabolic syndrome (e.g., fat mass regulation, vascular/endothelial remodeling, liver injury and repair, and carcinogenesis). The severity of nonalcoholic fatty liver disease (NAFLD) and the meta...

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Detalhes bibliográficos
Main Authors: Guy, Cynthia D., Suzuki, Ayako, Zdanowicz, Marzena, Abdelmalek, Manal F., Burchette, James, Unalp, Aynur, Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499103/
https://ncbi.nlm.nih.gov/pubmed/22213086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25559
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