Lapatinib-Binding Protein Kinases in the African Trypanosome: Identification of Cellular Targets for Kinase-Directed Chemical Scaffolds

Human African trypanosomiasis is caused by the eukaryotic microbe Trypanosoma brucei. To discover new drugs against the disease, one may use drugs in the clinic for other indications whose chemical scaffolds can be optimized via a medicinal chemistry campaign to achieve greater potency against the t...

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Autors principals: Katiyar, Samiksha, Kufareva, Irina, Behera, Ranjan, Thomas, Sarah M., Ogata, Yuko, Pollastri, Michael, Abagyan, Ruben, Mensa-Wilmot, Kojo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577790/
https://ncbi.nlm.nih.gov/pubmed/23437089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056150
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