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Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation

The key event in the mitochondrial pathway of apoptosis is the activation of Bax and Bak by BH3-only proteins through a molecular mechanism that is still a matter of debate. Here we studied interactions among anti- and proapoptotic proteins of the Bcl-2 family in living cells by using bimolecular fl...

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Autori principali: Vela, Laura, Gonzalo, Oscar, Naval, Javier, Marzo, Isabel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576097/
https://ncbi.nlm.nih.gov/pubmed/23283967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422204
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