Nalaganje...
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
The BH3-only proteins Bim and Bad bind to the antiapoptotic Bcl-2 proteins and induce apoptosis in wild-type cells and cells from either bax(−/−) or bak(−/−) animals. In contrast, constitutively active forms of Bim and Bad failed to induce apoptosis in bax(−/−)bak(−/−) cells. Expression of Bax resto...
Shranjeno v:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2001
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312722/ https://ncbi.nlm.nih.gov/pubmed/11410528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.897601 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|