BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
The BH3-only proteins Bim and Bad bind to the antiapoptotic Bcl-2 proteins and induce apoptosis in wild-type cells and cells from either bax(−/−) or bak(−/−) animals. In contrast, constitutively active forms of Bim and Bad failed to induce apoptosis in bax(−/−)bak(−/−) cells. Expression of Bax resto...
Na minha lista:
| Publicado no: | Genes Dev |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11410528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.897601 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|