BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK.
BH3 only proteins trigger cell death by interacting with pro- and anti-apoptotic members of the BCL-2 family of proteins. Here we report that BH3 peptides corresponding to the death domain of BH3-only proteins, which bind all the pro-survival BCL-2 family proteins, induce cell death in the absence o...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2009-05-01
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| Reeks: | PLoS ONE |
| Online toegang: | http://europepmc.org/articles/PMC2681411?pdf=render |
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