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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8(+) T Cells
IL-15 and IL-2 possess similar properties, including the ability to induce T cell proliferation. However, whereas IL-2 can promote apoptosis and limit CD8(+) memory T cell survival and proliferation, IL-15 helps maintain a memory CD8(+) T cell population and can inhibit apoptosis. We sought to deter...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC357036/ https://ncbi.nlm.nih.gov/pubmed/14762166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307298101 |
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