Inducible, reversible, and stable RNA interference in mammalian cells

RNA interference is a powerful genetic approach for efficiently silencing target genes. The existing method of gene suppression by the constitutive expression of short hairpin RNAs (shRNAs) allows analysis of the consequences of stably silencing genes but limits the analysis of genes essential for c...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gupta, Sunita, Schoer, Rebecca A., Egan, James E., Hannon, Gregory J., Mittal, Vivek
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2004
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC357029/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14762164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306111101
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