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Inducible, reversible, and stable RNA interference in mammalian cells

RNA interference is a powerful genetic approach for efficiently silencing target genes. The existing method of gene suppression by the constitutive expression of short hairpin RNAs (shRNAs) allows analysis of the consequences of stably silencing genes but limits the analysis of genes essential for c...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gupta, Sunita, Schoer, Rebecca A., Egan, James E., Hannon, Gregory J., Mittal, Vivek
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC357029/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14762164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306111101
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