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Inducible, reversible, and stable RNA interference in mammalian cells
RNA interference is a powerful genetic approach for efficiently silencing target genes. The existing method of gene suppression by the constitutive expression of short hairpin RNAs (shRNAs) allows analysis of the consequences of stably silencing genes but limits the analysis of genes essential for c...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC357029/ https://ncbi.nlm.nih.gov/pubmed/14762164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306111101 |
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