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Inducible, reversible, and stable RNA interference in mammalian cells

RNA interference is a powerful genetic approach for efficiently silencing target genes. The existing method of gene suppression by the constitutive expression of short hairpin RNAs (shRNAs) allows analysis of the consequences of stably silencing genes but limits the analysis of genes essential for c...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gupta, Sunita, Schoer, Rebecca A., Egan, James E., Hannon, Gregory J., Mittal, Vivek
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC357029/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14762164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306111101
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