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Stable suppression of gene expression by RNAi in mammalian cells

In a diverse group of organisms including plants, Caenorhabditis elegans, Drosophila, and trypanosomes, double-stranded RNA (dsRNA) is a potent trigger of gene silencing. In several model systems, this natural response has been developed into a powerful tool for the investigation of gene function. U...

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Bibliografiske detaljer
Main Authors: Paddison, Patrick J., Caudy, Amy A., Hannon, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122210/
https://ncbi.nlm.nih.gov/pubmed/11818553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032652399
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