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Stable suppression of gene expression by RNAi in mammalian cells

In a diverse group of organisms including plants, Caenorhabditis elegans, Drosophila, and trypanosomes, double-stranded RNA (dsRNA) is a potent trigger of gene silencing. In several model systems, this natural response has been developed into a powerful tool for the investigation of gene function. U...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Paddison, Patrick J., Caudy, Amy A., Hannon, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122210/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11818553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032652399
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