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RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

Introduction of exogenous double-stranded RNA (dsRNA) into Caenorhabditis elegans has been shown to specifically and potently disrupt the activity of genes containing homologous sequences. In this study we present evidence that the primary interference effects of dsRNA are post-transcriptional. Firs...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Montgomery, Mary K., Xu, SiQun, Fire, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9860998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15502
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