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The role of protein tyrosine phosphatase 1B in Ras signaling
Protein tyrosine phosphatase (PTP) 1B has been implicated as a negative regulator of multiple signaling pathways downstream of receptor tyrosine kinases. Inhibition of this enzyme was initially thought to potentially lead to increased oncogenic signaling and tumorigenesis. Surprisingly, we show that...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC357013/ https://ncbi.nlm.nih.gov/pubmed/14766979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0304242101 |
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