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Identification of a Nuclear Stat1 Protein Tyrosine Phosphatase

Upon interferon (IFN) stimulation, Stat1 becomes tyrosine phosphorylated and translocates into the nucleus, where it binds to DNA to activate transcription. The activity of Stat1 is dependent on tyrosine phosphorylation, and its inactivation in the nucleus is accomplished by a previously unknown pro...

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Publicado no:Mol Cell Biol
Principais autores: ten Hoeve, Johanna, de Jesus Ibarra-Sanchez, Maria, Fu, Yubin, Zhu, Wei, Tremblay, Michel, David, Michael, Shuai, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12138178/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.16.5662-5668.2002
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