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Identification of a Nuclear Stat1 Protein Tyrosine Phosphatase
Upon interferon (IFN) stimulation, Stat1 becomes tyrosine phosphorylated and translocates into the nucleus, where it binds to DNA to activate transcription. The activity of Stat1 is dependent on tyrosine phosphorylation, and its inactivation in the nucleus is accomplished by a previously unknown pro...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133976/ https://ncbi.nlm.nih.gov/pubmed/12138178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5662-5668.2002 |
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