Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways

Gene expression is regulated by DNA as well as histone modifications but the crosstalk and mechanistic link between these epigenetic signals are still poorly understood. Here we investigate the multi-domain protein Uhrf2 that is similar to Uhrf1, an essential cofactor of maintenance DNA methylation....

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Bibliografski detalji
Glavni autori: Pichler, Garwin, Wolf, Patricia, Schmidt, Christine S, Meilinger, Daniela, Schneider, Katrin, Frauer, Carina, Fellinger, Karin, Rottach, Andrea, Leonhardt, Heinrich
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2011
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569875/
https://ncbi.nlm.nih.gov/pubmed/21598301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23185
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