Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways

Gene expression is regulated by DNA as well as histone modifications but the crosstalk and mechanistic link between these epigenetic signals are still poorly understood. Here we investigate the multi-domain protein Uhrf2 that is similar to Uhrf1, an essential cofactor of maintenance DNA methylation....

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Pichler, Garwin, Wolf, Patricia, Schmidt, Christine S, Meilinger, Daniela, Schneider, Katrin, Frauer, Carina, Fellinger, Karin, Rottach, Andrea, Leonhardt, Heinrich
التنسيق: Artigo
اللغة:Inglês
منشور في: Wiley Subscription Services, Inc., A Wiley Company 2011
الموضوعات:
Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569875/
https://ncbi.nlm.nih.gov/pubmed/21598301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23185
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