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The multi-domain protein Np95 connects DNA methylation and histone modification

DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. Recently, Np95 (also known as UHRF1 or ICBP90) has been found to interact with Dnmt1 and to bind hemimethylated DNA, indicating together with genetic studies a cent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rottach, Andrea, Frauer, Carina, Pichler, Garwin, Bonapace, Ian Marc, Spada, Fabio, Leonhardt, Heinrich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847221/
https://ncbi.nlm.nih.gov/pubmed/20026581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1152
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