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The multi-domain protein Np95 connects DNA methylation and histone modification

DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. Recently, Np95 (also known as UHRF1 or ICBP90) has been found to interact with Dnmt1 and to bind hemimethylated DNA, indicating together with genetic studies a cent...

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Detalhes bibliográficos
Main Authors: Rottach, Andrea, Frauer, Carina, Pichler, Garwin, Bonapace, Ian Marc, Spada, Fabio, Leonhardt, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847221/
https://ncbi.nlm.nih.gov/pubmed/20026581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1152
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