KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1

Functional genomic elements are marked by characteristic DNA and histone modification signatures. How combinatorial chromatin modification states are recognized by epigenetic reader proteins and how this is linked to their biological function is largely unknown. Here we provide a detailed molecular...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Borgel, Julie, Tyl, Marek, Schiller, Karin, Pusztai, Zsofia, Dooley, Christopher M., Deng, Wen, Wooding, Carol, White, Richard J., Warnecke, Tobias, Leonhardt, Heinrich, Busch-Nentwich, Elisabeth M., Bartke, Till
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388433/
https://ncbi.nlm.nih.gov/pubmed/28180290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw979
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