The multi-domain protein Np95 connects DNA methylation and histone modification

DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. Recently, Np95 (also known as UHRF1 or ICBP90) has been found to interact with Dnmt1 and to bind hemimethylated DNA, indicating together with genetic studies a cent...

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Bibliografiske detaljer
Main Authors: Rottach, Andrea, Frauer, Carina, Pichler, Garwin, Bonapace, Ian Marc, Spada, Fabio, Leonhardt, Heinrich
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847221/
https://ncbi.nlm.nih.gov/pubmed/20026581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1152
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