Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1

Several mammalian proteins involved in chromatin and DNA modification contain CXXC zinc finger domains. We compared the structure and function of the CXXC domains in the DNA methyltransferase Dnmt1 and the methylcytosine dioxygenase Tet1. Sequence alignment showed that both CXXC domains have a very...

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Main Authors: Frauer, Carina, Rottach, Andrea, Meilinger, Daniela, Bultmann, Sebastian, Fellinger, Karin, Hasenöder, Stefan, Wang, Mengxi, Qin, Weihua, Söding, Johannes, Spada, Fabio, Leonhardt, Heinrich
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032784/
https://ncbi.nlm.nih.gov/pubmed/21311766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016627
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