Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1

Several mammalian proteins involved in chromatin and DNA modification contain CXXC zinc finger domains. We compared the structure and function of the CXXC domains in the DNA methyltransferase Dnmt1 and the methylcytosine dioxygenase Tet1. Sequence alignment showed that both CXXC domains have a very...

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Hlavní autoři: Frauer, Carina, Rottach, Andrea, Meilinger, Daniela, Bultmann, Sebastian, Fellinger, Karin, Hasenöder, Stefan, Wang, Mengxi, Qin, Weihua, Söding, Johannes, Spada, Fabio, Leonhardt, Heinrich
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032784/
https://ncbi.nlm.nih.gov/pubmed/21311766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016627
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