Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1

Several mammalian proteins involved in chromatin and DNA modification contain CXXC zinc finger domains. We compared the structure and function of the CXXC domains in the DNA methyltransferase Dnmt1 and the methylcytosine dioxygenase Tet1. Sequence alignment showed that both CXXC domains have a very...

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Autors principals: Frauer, Carina, Rottach, Andrea, Meilinger, Daniela, Bultmann, Sebastian, Fellinger, Karin, Hasenöder, Stefan, Wang, Mengxi, Qin, Weihua, Söding, Johannes, Spada, Fabio, Leonhardt, Heinrich
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032784/
https://ncbi.nlm.nih.gov/pubmed/21311766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016627
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