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Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways
Gene expression is regulated by DNA as well as histone modifications but the crosstalk and mechanistic link between these epigenetic signals are still poorly understood. Here we investigate the multi-domain protein Uhrf2 that is similar to Uhrf1, an essential cofactor of maintenance DNA methylation....
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3569875/ https://ncbi.nlm.nih.gov/pubmed/21598301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23185 |
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