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Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways

Gene expression is regulated by DNA as well as histone modifications but the crosstalk and mechanistic link between these epigenetic signals are still poorly understood. Here we investigate the multi-domain protein Uhrf2 that is similar to Uhrf1, an essential cofactor of maintenance DNA methylation....

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Main Authors: Pichler, Garwin, Wolf, Patricia, Schmidt, Christine S, Meilinger, Daniela, Schneider, Katrin, Frauer, Carina, Fellinger, Karin, Rottach, Andrea, Leonhardt, Heinrich
Formáid: Artigo
Teanga:Inglês
Foilsithe: Wiley Subscription Services, Inc., A Wiley Company 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569875/
https://ncbi.nlm.nih.gov/pubmed/21598301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23185
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