Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

BACKGROUND: Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic stem-cell transplantation (HSCT). The chemokine receptor CCR5 appears to play a role in alloreactivity. We tested whether CCR5 blockade would be safe and limit GVHD in humans. METHODS: We tested th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Reshef, Ran, Luger, Selina M., Hexner, Elizabeth O., Loren, Alison W., Frey, Noelle V., Nasta, Sunita D., Goldstein, Steven C., Stadtmauer, Edward A., Smith, Jacqueline, Bailey, Sarah, Mick, Rosemarie, Heitjan, Daniel F., Emerson, Stephen G., Hoxie, James A., Vonderheide, Robert H., Porter, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568501/
https://ncbi.nlm.nih.gov/pubmed/22784116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1201248
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