Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

BACKGROUND: Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic stem-cell transplantation (HSCT). The chemokine receptor CCR5 appears to play a role in alloreactivity. We tested whether CCR5 blockade would be safe and limit GVHD in humans. METHODS: We tested th...

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Bibliografiset tiedot
Päätekijät: Reshef, Ran, Luger, Selina M., Hexner, Elizabeth O., Loren, Alison W., Frey, Noelle V., Nasta, Sunita D., Goldstein, Steven C., Stadtmauer, Edward A., Smith, Jacqueline, Bailey, Sarah, Mick, Rosemarie, Heitjan, Daniel F., Emerson, Stephen G., Hoxie, James A., Vonderheide, Robert H., Porter, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568501/
https://ncbi.nlm.nih.gov/pubmed/22784116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1201248
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