Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

BACKGROUND: Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic stem-cell transplantation (HSCT). The chemokine receptor CCR5 appears to play a role in alloreactivity. We tested whether CCR5 blockade would be safe and limit GVHD in humans. METHODS: We tested th...

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Detaylı Bibliyografya
Asıl Yazarlar: Reshef, Ran, Luger, Selina M., Hexner, Elizabeth O., Loren, Alison W., Frey, Noelle V., Nasta, Sunita D., Goldstein, Steven C., Stadtmauer, Edward A., Smith, Jacqueline, Bailey, Sarah, Mick, Rosemarie, Heitjan, Daniel F., Emerson, Stephen G., Hoxie, James A., Vonderheide, Robert H., Porter, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568501/
https://ncbi.nlm.nih.gov/pubmed/22784116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1201248
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