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Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease
BACKGROUND: Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic stem-cell transplantation (HSCT). The chemokine receptor CCR5 appears to play a role in alloreactivity. We tested whether CCR5 blockade would be safe and limit GVHD in humans. METHODS: We tested th...
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| Huvudupphovsmän: | , , , , , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568501/ https://ncbi.nlm.nih.gov/pubmed/22784116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1201248 |
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