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Ligand-dependent Conformational Changes in the Clamp Region of the Cardiac Ryanodine Receptor

Global conformational changes in the three-dimensional structure of the Ca(2+) release channel/ryanodine receptor (RyR) occur upon ligand activation. A number of ligands are able to activate the RyR channel, but whether these structurally diverse ligands induce the same or different conformational c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tian, Xixi, Liu, Yingjie, Liu, Ying, Wang, Ruiwu, Wagenknecht, Terence, Liu, Zheng, Chen, S. R. Wayne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567658/
https://ncbi.nlm.nih.gov/pubmed/23258540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427864
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