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Ligand-dependent Conformational Changes in the Clamp Region of the Cardiac Ryanodine Receptor
Global conformational changes in the three-dimensional structure of the Ca(2+) release channel/ryanodine receptor (RyR) occur upon ligand activation. A number of ligands are able to activate the RyR channel, but whether these structurally diverse ligands induce the same or different conformational c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567658/ https://ncbi.nlm.nih.gov/pubmed/23258540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427864 |
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