Calmodulin-binding Locations on the Skeletal and Cardiac Ryanodine Receptors

Ryanodine receptor types 1 (RyR1) and 2 (RyR2) are calcium release channels that are highly enriched in skeletal and cardiac muscle, respectively, where they play an essential role in excitation-contraction coupling. Apocalmodulin (apo-CaM) weakly activates RyR1 but inhibits RyR2, whereas Ca(2+)-cal...

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Detalhes bibliográficos
Main Authors: Huang, Xiaojun, Fruen, Bradley, Farrington, Dinah T., Wagenknecht, Terence, Liu, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436284/
https://ncbi.nlm.nih.gov/pubmed/22773841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383109
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