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Calmodulin-binding Locations on the Skeletal and Cardiac Ryanodine Receptors
Ryanodine receptor types 1 (RyR1) and 2 (RyR2) are calcium release channels that are highly enriched in skeletal and cardiac muscle, respectively, where they play an essential role in excitation-contraction coupling. Apocalmodulin (apo-CaM) weakly activates RyR1 but inhibits RyR2, whereas Ca(2+)-cal...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436284/ https://ncbi.nlm.nih.gov/pubmed/22773841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383109 |
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