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Genome-wide study of methotrexate clearance replicates SLCO1B1
Methotrexate clearance can influence the cure of and toxicity in children with acute lymphoblastic leukemia (ALL). We estimated methotrexate plasma clearance for 1279 patients with ALL treated with methotrexate (24-hour infusion of a 1 g/m(2) dose or 4-hour infusion of a 2 g/m(2) dose) on the Childr...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567337/ https://ncbi.nlm.nih.gov/pubmed/23233662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-452839 |
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