Conformational Transition Pathway in the Activation Process of Allosteric Glucokinase

Glucokinase (GK) is a glycolytic enzyme that plays an important role in regulating blood glucose level, thus acting as a potentially attractive target for drug discovery in the treatment of diabetes of the young type 2 and persistent hyperinsulinemic hypoglycemia of infancy. To characterize the acti...

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Autors principals: Huang, Min, Lu, Shaoyong, Shi, Ting, Zhao, Yaxue, Chen, Yingyi, Li, Xiaobai, Liu, Xinyi, Huang, Zhimin, Zhang, Jian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567010/
https://ncbi.nlm.nih.gov/pubmed/23409066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055857
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