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Conformational transition pathway in the allosteric process of human glucokinase
Glucokinase (GK) is an important enzyme for regulating blood glucose levels and a potentially attractive target for diabetes of the young type 2 and persistent hyperinsulinemic hypoglycemia of infancy. To characterize the conformational transition of GK from the closed state to the superopen state,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569170/ https://ncbi.nlm.nih.gov/pubmed/16938872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605738103 |
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