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Conformational transition of amyloid β-peptide

The amyloid β-peptides (Aβs), containing 39–43 residues, are the key protein components of amyloid deposits in Alzheimer's disease. To structurally characterize the dynamic behavior of Aβ(40), 12 independent long-time molecular dynamics (MD) simulations for a total of 850 ns were performed on b...

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Detalhes bibliográficos
Main Authors: Xu, Yechun, Shen, Jianhua, Luo, Xiaomin, Zhu, Weiliang, Chen, Kaixian, Ma, Jianpeng, Jiang, Hualiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556260/
https://ncbi.nlm.nih.gov/pubmed/15800039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501218102
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