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Unsuspected pathway of the allosteric transition in hemoglobin
Large conformational transitions play an essential role in the function of many proteins, but experiments do not provide the atomic details of the path followed in going from one end structure to the other. For the hemoglobin tetramer, the transition path between the unliganded (T) and tetraoxygenat...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078355/ https://ncbi.nlm.nih.gov/pubmed/21415366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011995108 |
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