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Collective Dynamics Underlying Allosteric Transitions in Hemoglobin
Hemoglobin is the prototypic allosteric protein. Still, its molecular allosteric mechanism is not fully understood. To elucidate the mechanism of cooperativity on an atomistic level, we developed a novel computational technique to analyse the coupling of tertiary and quaternary motions. From Molecul...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777908/ https://ncbi.nlm.nih.gov/pubmed/24068910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003232 |
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