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Collective Dynamics Underlying Allosteric Transitions in Hemoglobin

Hemoglobin is the prototypic allosteric protein. Still, its molecular allosteric mechanism is not fully understood. To elucidate the mechanism of cooperativity on an atomistic level, we developed a novel computational technique to analyse the coupling of tertiary and quaternary motions. From Molecul...

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Detalles Bibliográficos
Main Authors: Vesper, Martin D., de Groot, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777908/
https://ncbi.nlm.nih.gov/pubmed/24068910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003232
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