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Collective Dynamics Underlying Allosteric Transitions in Hemoglobin

Hemoglobin is the prototypic allosteric protein. Still, its molecular allosteric mechanism is not fully understood. To elucidate the mechanism of cooperativity on an atomistic level, we developed a novel computational technique to analyse the coupling of tertiary and quaternary motions. From Molecul...

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Bibliografische gegevens
Hoofdauteurs: Vesper, Martin D., de Groot, Bert L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777908/
https://ncbi.nlm.nih.gov/pubmed/24068910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003232
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