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Conformational Transition Pathway in the Activation Process of Allosteric Glucokinase
Glucokinase (GK) is a glycolytic enzyme that plays an important role in regulating blood glucose level, thus acting as a potentially attractive target for drug discovery in the treatment of diabetes of the young type 2 and persistent hyperinsulinemic hypoglycemia of infancy. To characterize the acti...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567010/ https://ncbi.nlm.nih.gov/pubmed/23409066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055857 |
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