Dependency of Calcium Alternans on Ryanodine Receptor Refractoriness

BACKGROUND: Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium released from the sarcoplasmic reticulum (SR). However, the relationship between calcium alternans and refractoriness of the SR calcium release channel (RyR2) remains elusive....

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Bibliographic Details
Main Authors: Alvarez-Lacalle, Enric, Cantalapiedra, Inma R., Peñaranda, Angelina, Cinca, Juan, Hove-Madsen, Leif, Echebarria, Blas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563653/
https://ncbi.nlm.nih.gov/pubmed/23390511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055042
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