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Dependency of Calcium Alternans on Ryanodine Receptor Refractoriness

BACKGROUND: Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium released from the sarcoplasmic reticulum (SR). However, the relationship between calcium alternans and refractoriness of the SR calcium release channel (RyR2) remains elusive....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alvarez-Lacalle, Enric, Cantalapiedra, Inma R., Peñaranda, Angelina, Cinca, Juan, Hove-Madsen, Leif, Echebarria, Blas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563653/
https://ncbi.nlm.nih.gov/pubmed/23390511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055042
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