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Dependency of Calcium Alternans on Ryanodine Receptor Refractoriness

BACKGROUND: Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium released from the sarcoplasmic reticulum (SR). However, the relationship between calcium alternans and refractoriness of the SR calcium release channel (RyR2) remains elusive....

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Detalhes bibliográficos
Main Authors: Alvarez-Lacalle, Enric, Cantalapiedra, Inma R., Peñaranda, Angelina, Cinca, Juan, Hove-Madsen, Leif, Echebarria, Blas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563653/
https://ncbi.nlm.nih.gov/pubmed/23390511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055042
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