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Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes

Ventricular contraction is roughly proportional to the amount of calcium released from the Sarcoplasmic Reticulum (SR) during systole. While it is rather straightforward to measure calcium levels and contractibility under different physiological conditions, the complexity of calcium handling during...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Conesa, David, Echebarria, Blas, Peñaranda, Angelina, Cantalapiedra, Inmaculada R., Shiferaw, Yohannes, Alvarez-Lacalle, Enrique
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316341/
https://ncbi.nlm.nih.gov/pubmed/32502205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007572
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