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Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes

Ventricular contraction is roughly proportional to the amount of calcium released from the Sarcoplasmic Reticulum (SR) during systole. While it is rather straightforward to measure calcium levels and contractibility under different physiological conditions, the complexity of calcium handling during...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Conesa, David, Echebarria, Blas, Peñaranda, Angelina, Cantalapiedra, Inmaculada R., Shiferaw, Yohannes, Alvarez-Lacalle, Enrique
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316341/
https://ncbi.nlm.nih.gov/pubmed/32502205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007572
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