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Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes

Ventricular contraction is roughly proportional to the amount of calcium released from the Sarcoplasmic Reticulum (SR) during systole. While it is rather straightforward to measure calcium levels and contractibility under different physiological conditions, the complexity of calcium handling during...

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Bibliografische gegevens
Gepubliceerd in:PLoS Comput Biol
Hoofdauteurs: Conesa, David, Echebarria, Blas, Peñaranda, Angelina, Cantalapiedra, Inmaculada R., Shiferaw, Yohannes, Alvarez-Lacalle, Enrique
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316341/
https://ncbi.nlm.nih.gov/pubmed/32502205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007572
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