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Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes

Ventricular contraction is roughly proportional to the amount of calcium released from the Sarcoplasmic Reticulum (SR) during systole. While it is rather straightforward to measure calcium levels and contractibility under different physiological conditions, the complexity of calcium handling during...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Conesa, David, Echebarria, Blas, Peñaranda, Angelina, Cantalapiedra, Inmaculada R., Shiferaw, Yohannes, Alvarez-Lacalle, Enrique
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316341/
https://ncbi.nlm.nih.gov/pubmed/32502205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007572
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