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Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload
Myocyte apoptosis is considered a major mechanism in the pathogenesis of heart failure. Accordingly, manipulations that inhibit apoptosis are assumed to preserve cardiac function by maintaining myocyte numbers. We tested this assumption by examining the effects of caspase inhibition (CI) on cardiac...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563433/ https://ncbi.nlm.nih.gov/pubmed/23277091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0324-y |
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