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Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload
We tested the possibility that proteasome inhibition may reverse preexisting cardiac hypertrophy and improve remodeling upon pressure overload. Mice were submitted to aortic banding and followed up for 3 wk. The proteasome inhibitor epoxomicin (0.5 mg/kg) or the vehicle was injected daily, starting...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593511/ https://ncbi.nlm.nih.gov/pubmed/18676687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00532.2008 |
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