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Apoptosis in severe, compensated pressure overload predominates in nonmyocytes and is related to the hypertrophy but not function

It is widely held that myocyte apoptosis in left ventricular hypertrophy (LVH) contributes to left ventricle (LV) dysfunction and heart failure. The main goal of this investigation was to determine if there is a statistical relationship among LV hypertrophy, apoptosis and LV function, and importantl...

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Main Authors: Gelpi, Ricardo J., Park, Misun, Gao, Shumin, Dhar, Sunil, Vatner, Dorothy E., Vatner, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302193/
https://ncbi.nlm.nih.gov/pubmed/21148760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00998.2010
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