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Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload

Myocyte apoptosis is considered a major mechanism in the pathogenesis of heart failure. Accordingly, manipulations that inhibit apoptosis are assumed to preserve cardiac function by maintaining myocyte numbers. We tested this assumption by examining the effects of caspase inhibition (CI) on cardiac...

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Detalhes bibliográficos
Main Authors: Park, Misun, Vatner, Stephen F., Yan, Lin, Gao, Shumin, Yoon, Seunghun, Lee, Grace Jung Ah, Xie, Lai-Hua, Kitsis, Richard N., Vatner, Dorothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563433/
https://ncbi.nlm.nih.gov/pubmed/23277091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0324-y
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