Inhibitors of Dengue Virus and West Nile Virus Proteases Based on the Aminobenzamide Scaffold

Dengue and West Nile viruses (WNV) are mosquito-borne members of flaviviruses that cause significant morbidity and mortality. There is no approved vaccine or antiviral drugs for human use to date. In this study, a series of functionalized meta and para aminobenzamide derivatives were synthesized and...

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Hauptverfasser: Aravapalli, Sridhar, Lai, Huiguo, Teramoto, Tadahisa, Alliston, Kevin R., Lushington, Gerald H., Ferguson, Eron L., Padmanabhan, R., Groutas, William C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563422/
https://ncbi.nlm.nih.gov/pubmed/22632792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.04.055
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